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The NRF-2 pathway aids the antioxidant mechanism with necessary compounds to protect against the OS, which will not be found in excessive situations and which can be maintained under control [8,9]

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In 2020, a related study (28) demonstrated that overexpression of miR-140-3p inhibited the proliferation of human cervical cancer cells by targeting down-regulation of RRM2 inducing cell cycle arrest and early apoptosis, while decreasing BCL-2 protein levels and inducing a significant increase in BAX and caspase-3 protein levels

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PMCID: PMC5588976